non-trigger anesthesia management in a patient with leigh’s syndrome presenting for dental rehabilitation

case presentation we report a male patient with leigh’s syndrome and a family history suggestive of unknown hypotonia and malignant hyperthermia presenting for dental rehabilitation. conclusions dexmedetomidine with remifentanil can be used with no complication in this senerio. introduction usually presenting in infancy, leigh’s syndrome is an inherited condition often manifesting with seizures, ataxia, developmental delay, and dysarthria. the disorder is rare, appearing in approximately 1 in 40,000 live births. consequently, providing these patients with a suitable plan by which to administer anesthetics remains problematic.